{"id":6391,"date":"2024-05-20T09:01:23","date_gmt":"2024-05-20T09:01:23","guid":{"rendered":"http:\/\/medexperts.pro\/?p=6391"},"modified":"2024-05-20T09:25:54","modified_gmt":"2024-05-20T09:25:54","slug":"what-to-know-about-ozempic-and-other-drugs-used-for-weight-loss","status":"publish","type":"post","link":"https:\/\/medexperts.pro\/?p=6391","title":{"rendered":"What to Know About Ozempic and Other Drugs Used for Weight Loss"},"content":{"rendered":"<div><\/div>\n<p id=\"article-summary\" class=\"css-1n0orw4 e1wiw3jv0\">How they work, what to expect when taking them and what the future holds.<\/p>\n<section class=\"meteredContent css-1r7ky0e\">\n<div class=\"css-s99gbd StoryBodyCompanionColumn\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">News around drugs like Ozempic moves fast: There\u2019s a steady drumbeat of new studies, new regulatory approvals, new shortages, new insurance hurdles. Here\u2019s a primer on Ozempic and other popular drugs being widely used for diabetes and weight loss.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\n<h2 class=\"css-kypbrf eoo0vm40\" id=\"link-4cea9431\">How do drugs like Ozempic work?<\/h2>\n<p class=\"css-at9mc1 evys1bk0\">Ozempic belongs to a class of medications called GLP-1 receptor agonists, named after a hormone in the human body that they are designed to imitate. <\/p>\n<p class=\"css-at9mc1 evys1bk0\">In 2017, the Food and Drug Administration <a class=\"css-yywogo\" href=\"https:\/\/www.novonordisk.com\/content\/nncorp\/global\/en\/news-and-media\/news-and-ir-materials\/news-details.html?id=712\" title rel=\"noopener noreferrer\" target=\"_blank\">approved Ozempic<\/a> to treat Type 2 diabetes, but people have also used the drug off-label to lose weight. In the last few years, other similar drugs have hit the market: <a class=\"css-yywogo\" href=\"https:\/\/www.nytimes.com\/2023\/10\/05\/well\/live\/wegovy-shortage-ozempic-fda.html\" title>Wegovy,<\/a> a drug approved for weight loss and to reduce the risk of cardiovascular issues in some adults; <a class=\"css-yywogo\" href=\"https:\/\/www.nytimes.com\/2023\/04\/11\/well\/live\/ozempic-mounjaro-weight-loss-diabetes.html\" title>Mounjaro,<\/a> approved for Type 2 diabetes; and <a class=\"css-yywogo\" href=\"https:\/\/www.nytimes.com\/2023\/11\/08\/well\/zepbound-mounjaro-weight-loss.html\" title>Zepbound<\/a>, authorized for weight loss. These medications are all weekly shots.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Both Wegovy and Ozempic contain semaglutide, which mimics the hormone GLP-1 to stimulate insulin production in the pancreas and slow down stomach emptying, making people feel fuller faster, and for longer. Mounjaro and Zepbound work similarly, but they use tirzepatide (rather than semaglutide) to simulate both GLP-1 and a second hormone, GIP.<\/p>\n<\/div>\n<\/div>\n<div><\/div>\n<div class=\"css-s99gbd StoryBodyCompanionColumn\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">Crucially, semaglutide and tirzepatide also target the brain: They curb hunger signals, silencing what many users have called \u201c<a class=\"css-yywogo\" href=\"https:\/\/www.nytimes.com\/2023\/06\/21\/well\/eat\/ozempic-food-noise.html\" title>food noise<\/a>.\u201d<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The drugs don\u2019t work for everyone. In clinical trials, a small fraction of participants have not lost significant weight or seen meaningful improvements in blood sugar control. \u201cWe haven\u2019t quite figured out yet who will respond well,\u201d said Dr. Scott Hagan, an assistant professor of medicine at the University of Washington who studies obesity.<\/p>\n<div class=\"css-1336jj\">\n<div class=\"css-121kum4\">\n<div class=\"css-171d1bw\"><\/div>\n<div class=\"css-asuuk5\">\n<div class=\"css-7axq9l\" data-testid=\"optimistic-truncator-noscript\">\n<div data-testid=\"optimistic-truncator-noscript-message\" class=\"css-6yo1no\">\n<p class=\"css-3kpklk\">We are having trouble retrieving the article content.<\/p>\n<p class=\"css-3kpklk\">Please enable JavaScript in your browser settings.<\/p>\n<\/div>\n<\/div>\n<div class=\"css-1dv1kvn\" id=\"optimistic-truncator-a11y\">\n<hr \/>\n<p>Thank you for your patience while we verify access. If you are in Reader mode please exit and\u00a0<a href=\"https:\/\/myaccount.nytimes.com\/auth\/login?response_type=cookie&amp;client_id=vi&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F05%2F20%2Fwell%2Flive%2Fozempic-weight-loss-drugs.html&amp;asset=opttrunc\">log into<\/a>\u00a0your Times account, or\u00a0<a href=\"https:\/\/www.nytimes.com\/subscription?campaignId=89WYR&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F05%2F20%2Fwell%2Flive%2Fozempic-weight-loss-drugs.html\">subscribe<\/a>\u00a0for all of The Times.<\/p>\n<hr \/>\n<\/div>\n<div class=\"css-1g71tqy\">\n<div data-testid=\"optimistic-truncator-message\" class=\"css-6yo1no\">\n<p class=\"css-3kpklk\">Thank you for your patience while we verify access.<\/p>\n<p class=\"css-3kpklk\">Already a subscriber?\u00a0<a data-testid=\"log-in-link\" class=\"css-z5ryv4\" href=\"https:\/\/myaccount.nytimes.com\/auth\/login?response_type=cookie&amp;client_id=vi&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F05%2F20%2Fwell%2Flive%2Fozempic-weight-loss-drugs.html&amp;asset=opttrunc\">Log in<\/a>.<\/p>\n<p class=\"css-3kpklk\">Want all of The Times?\u00a0<a data-testid=\"subscribe-link\" class=\"css-z5ryv4\" href=\"https:\/\/www.nytimes.com\/subscription?campaignId=89WYR&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F05%2F20%2Fwell%2Flive%2Fozempic-weight-loss-drugs.html\">Subscribe<\/a>.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>How they work, what to expect when taking them and what the future holds.News around drugs like Ozempic moves fast: There\u2019s a steady drumbeat of new studies, new regulatory approvals, new shortages, new insurance hurdles. Here\u2019s a primer on Ozempic and other popular drugs being widely used for diabetes and weight loss. How do drugs like Ozempic work?Ozempic belongs to a class of medications called GLP-1 receptor agonists, named after a hormone in the human body that they are designed to imitate. In 2017, the Food and Drug Administration approved Ozempic to treat Type 2 diabetes, but people have also used the drug off-label to lose weight. In the last few years, other similar drugs have hit the market: Wegovy, a drug approved for weight loss and to reduce the risk of cardiovascular issues in some adults; Mounjaro, approved for Type 2 diabetes; and Zepbound, authorized for weight loss. These medications are all weekly shots.Both Wegovy and Ozempic contain semaglutide, which mimics the hormone GLP-1 to stimulate insulin production in the pancreas and slow down stomach emptying, making people feel fuller faster, and for longer. Mounjaro and Zepbound work similarly, but they use tirzepatide (rather than semaglutide) to simulate both GLP-1 and a second hormone, GIP.Crucially, semaglutide and tirzepatide also target the brain: They curb hunger signals, silencing what many users have called \u201cfood noise.\u201dThe drugs don\u2019t work for everyone. In clinical trials, a small fraction of participants have not lost significant weight or seen meaningful improvements in blood sugar control. \u201cWe haven\u2019t quite figured out yet who will respond well,\u201d said Dr. Scott Hagan, an assistant professor of medicine at the University of Washington who studies obesity.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and\u00a0log into\u00a0your Times account, or\u00a0subscribe\u00a0for all of The Times.Thank you for your patience while we verify access.Already a subscriber?\u00a0Log in.Want all of The Times?\u00a0Subscribe.<\/p>\n","protected":false},"author":1,"featured_media":6393,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-6391","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle"],"_links":{"self":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/6391","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6391"}],"version-history":[{"count":2,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/6391\/revisions"}],"predecessor-version":[{"id":6394,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/6391\/revisions\/6394"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/media\/6393"}],"wp:attachment":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6391"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6391"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6391"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}