{"id":2538,"date":"2024-03-20T08:00:07","date_gmt":"2024-03-20T09:00:07","guid":{"rendered":"https:\/\/medexperts.pro\/?p=2538"},"modified":"2024-03-20T09:24:52","modified_gmt":"2024-03-20T09:24:52","slug":"why-do-we-age","status":"publish","type":"post","link":"https:\/\/medexperts.pro\/?p=2538","title":{"rendered":"Why Do We Age?"},"content":{"rendered":"<div><\/div>\n<p id=\"article-summary\" class=\"css-1n0orw4 e1wiw3jv0\">Scientists are investigating how our biology changes as the years add up, and whether there are ways to stop it.<\/p>\n<section class=\"meteredContent css-1r7ky0e\">\n<div class=\"css-s99gbd StoryBodyCompanionColumn\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">According to some estimates, consumers spend $62 billion a year on \u201canti-aging\u201d treatments. But while creams, hair dyes and Botox can give the impression of youth, none of them can roll back the hands of time.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Scientists are working to understand the biological causes of aging in the hope of one day being able to offer tools to slow or stop its visible signs and, more important, age-related diseases. These underlying mechanisms are often called \u201c<a class=\"css-yywogo\" href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(22)01377-0\" title rel=\"noopener noreferrer\" target=\"_blank\">the hallmarks of aging<\/a>.\u201d Many fall into two broad categories: general wear and tear on a cellular level, and the body\u2019s decreasing ability to remove old or dysfunctional cells and proteins.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cThe crucial thing about the hallmarks is that they are things that go wrong during aging, and if you reverse them,\u201d you stand to live longer or be healthier while you age, said Dame Linda Partridge, a professorial research fellow in the division of biosciences at University College London who helped develop the aging hallmarks framework.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">So far, the research has primarily been conducted in animals, but experts are gradually expanding into humans. In the meantime, understanding how aging works can help us put advice and information about the latest \u201cbreakthrough\u201d into context, said Venki Ramakrishnan, a biochemist and Nobel laureate who wrote about many of the hallmarks of aging in his new book, \u201cWhy We Die: The New Science of Aging and the Quest for Immortality.\u201d<\/p>\n<\/div>\n<\/div>\n<div><\/div>\n<div class=\"css-s99gbd StoryBodyCompanionColumn\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">We asked experts about the hallmarks of aging, how they can lead to disease and how scientists are attempting to modify them. Not all of the hallmarks are listed here, but two of the main themes are highlighted below.<\/p>\n<h2 class=\"css-kypbrf eoo0vm40\" id=\"link-62295b5d\">Wear and Tear<\/h2>\n<p class=\"css-at9mc1 evys1bk0\">Many age-related changes start with our cells, and even our genes, acquiring damage and acting up as we get older.<\/p>\n<div class=\"css-1336jj\">\n<div class=\"css-121kum4\">\n<div class=\"css-171d1bw\"><\/div>\n<div class=\"css-asuuk5\">\n<div class=\"css-7axq9l\" data-testid=\"optimistic-truncator-noscript\">\n<div data-testid=\"optimistic-truncator-noscript-message\" class=\"css-6yo1no\">\n<p class=\"css-3kpklk\">We are having trouble retrieving the article content.<\/p>\n<p class=\"css-3kpklk\">Please enable JavaScript in your browser settings.<\/p>\n<\/div>\n<\/div>\n<div class=\"css-1dv1kvn\" id=\"optimistic-truncator-a11y\">\n<hr \/>\n<p>Thank you for your patience while we verify access. If you are in Reader mode please exit and\u00a0<a href=\"https:\/\/myaccount.nytimes.com\/auth\/login?response_type=cookie&amp;client_id=vi&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F03%2F20%2Fwell%2Flive%2Faging-biology-dna.html&amp;asset=opttrunc\">log into<\/a>\u00a0your Times account, or\u00a0<a href=\"https:\/\/www.nytimes.com\/subscription?campaignId=89WYR&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F03%2F20%2Fwell%2Flive%2Faging-biology-dna.html\">subscribe<\/a>\u00a0for all of The Times.<\/p>\n<hr \/>\n<\/div>\n<div class=\"css-1g71tqy\">\n<div data-testid=\"optimistic-truncator-message\" class=\"css-6yo1no\">\n<p class=\"css-3kpklk\">Thank you for your patience while we verify access.<\/p>\n<p class=\"css-3kpklk\">Already a subscriber?\u00a0<a data-testid=\"log-in-link\" class=\"css-z5ryv4\" href=\"https:\/\/myaccount.nytimes.com\/auth\/login?response_type=cookie&amp;client_id=vi&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F03%2F20%2Fwell%2Flive%2Faging-biology-dna.html&amp;asset=opttrunc\">Log in<\/a>.<\/p>\n<p class=\"css-3kpklk\">Want all of The Times?\u00a0<a data-testid=\"subscribe-link\" class=\"css-z5ryv4\" href=\"https:\/\/www.nytimes.com\/subscription?campaignId=89WYR&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F03%2F20%2Fwell%2Flive%2Faging-biology-dna.html\">Subscribe<\/a>.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Scientists are investigating how our biology changes as the years add up, and whether there are ways to stop it.According to some estimates, consumers spend $62 billion a year on \u201canti-aging\u201d treatments. But while creams, hair dyes and Botox can give the impression of youth, none of them can roll back the hands of time.Scientists are working to understand the biological causes of aging in the hope of one day being able to offer tools to slow or stop its visible signs and, more important, age-related diseases. These underlying mechanisms are often called \u201cthe hallmarks of aging.\u201d Many fall into two broad categories: general wear and tear on a cellular level, and the body\u2019s decreasing ability to remove old or dysfunctional cells and proteins.\u201cThe crucial thing about the hallmarks is that they are things that go wrong during aging, and if you reverse them,\u201d you stand to live longer or be healthier while you age, said Dame Linda Partridge, a professorial research fellow in the division of biosciences at University College London who helped develop the aging hallmarks framework.So far, the research has primarily been conducted in animals, but experts are gradually expanding into humans. In the meantime, understanding how aging works can help us put advice and information about the latest \u201cbreakthrough\u201d into context, said Venki Ramakrishnan, a biochemist and Nobel laureate who wrote about many of the hallmarks of aging in his new book, \u201cWhy We Die: The New Science of Aging and the Quest for Immortality.\u201dWe asked experts about the hallmarks of aging, how they can lead to disease and how scientists are attempting to modify them. Not all of the hallmarks are listed here, but two of the main themes are highlighted below.Wear and TearMany age-related changes start with our cells, and even our genes, acquiring damage and acting up as we get older.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and\u00a0log into\u00a0your Times account, or\u00a0subscribe\u00a0for all of The Times.Thank you for your patience while we verify access.Already a subscriber?\u00a0Log in.Want all of The Times?\u00a0Subscribe.<\/p>\n","protected":false},"author":1,"featured_media":2540,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-2538","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle"],"_links":{"self":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/2538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2538"}],"version-history":[{"count":2,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/2538\/revisions"}],"predecessor-version":[{"id":2541,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/2538\/revisions\/2541"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/media\/2540"}],"wp:attachment":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}