{"id":18343,"date":"2024-12-13T15:12:23","date_gmt":"2024-12-13T16:12:23","guid":{"rendered":"http:\/\/medexperts.pro\/?p=18343"},"modified":"2024-12-13T16:26:21","modified_gmt":"2024-12-13T16:26:21","slug":"what-the-polio-vaccine-has-meant-for-public-health","status":"publish","type":"post","link":"https:\/\/medexperts.pro\/?p=18343","title":{"rendered":"What the Polio Vaccine Has Meant for Public Health"},"content":{"rendered":"
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A lawyer working with Robert F. Kennedy Jr. has asked the F.D.A. to withdraw approval of the current shot because it hasn\u2019t been tested against a placebo. Scientists say such a test would be unethical.<\/p>\n

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On the day in 1955 that Jonas Salk\u2019s polio vaccine was pronounced \u201c80 to 90 percent effective\u201d against the form of the disease that caused paralysis, 500 medical scientists and 150 reporters jammed into an auditorium at the University of Michigan for the announcement. Pots clanged, horns honked and factory whistles blew around the country.<\/p>\n

In the seven decades since, polio \u2014 a disease that once killed or paralyzed<\/a> more than half a million people around the world each year \u2014 has been vanquished in the United States.<\/p>\n

A lawyer advising Robert F. Kennedy Jr. has asked t<\/a>he Food and Drug Administration to revoke its approval of the current polio vaccine, a successor to the Salk vaccine, because it has not been tested against a placebo.<\/p>\n

Experts say the move would be disastrous, because the polio virus is still around.<\/p>\n

\u201cWe would have big outbreaks of polio,\u201d warned Dr. Walter Orenstein, who ran immunization programs for the Centers for Disease Control and Prevention in the late 1980s and 1990s. Because some people infected with polio are asymptomatic, Dr. Orenstein said, the virus could spread through the population unnoticed \u2014 until people started getting paralyzed.<\/p>\n<\/div>\n<\/div>\n

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The Salk vaccine was tested against a placebo in 1.8 million American first- and second-grade schoolchildren in a so-called double-blind placebo-controlled trial \u2014 the gold standard in American medicine, in which half the study subjects get an inert vaccine and doctors, parents and patients did not know who got which.<\/p>\n

Salk himself objected to the use of a placebo during the clinical trial; he couldn\u2019t imagine depriving a child of a lifesaving vaccine. As the petition before the F.D.A. notes, the current vaccine, manufactured by Sanofi, was not tested against a placebo; scientists and doctors almost universally agree that withholding a lifesaving vaccine would be unethical.<\/p>\n

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A lawyer working with Robert F. Kennedy Jr. has asked the F.D.A. to withdraw approval of the current shot because it hasn\u2019t been tested against a placebo. Scientists say such a test would be unethical.On the day in 1955 that Jonas Salk\u2019s polio vaccine was pronounced \u201c80 to 90 percent effective\u201d against the form of the disease that caused paralysis, 500 medical scientists and 150 reporters jammed into an auditorium at the University of Michigan for the announcement. Pots clanged, horns honked and factory whistles blew around the country.In the seven decades since, polio \u2014 a disease that once killed or paralyzed more than half a million people around the world each year \u2014 has been vanquished in the United States.A lawyer advising Robert F. Kennedy Jr. has asked the Food and Drug Administration to revoke its approval of the current polio vaccine, a successor to the Salk vaccine, because it has not been tested against a placebo.Experts say the move would be disastrous, because the polio virus is still around.\u201cWe would have big outbreaks of polio,\u201d warned Dr. Walter Orenstein, who ran immunization programs for the Centers for Disease Control and Prevention in the late 1980s and 1990s. Because some people infected with polio are asymptomatic, Dr. Orenstein said, the virus could spread through the population unnoticed \u2014 until people started getting paralyzed.The Salk vaccine was tested against a placebo in 1.8 million American first- and second-grade schoolchildren in a so-called double-blind placebo-controlled trial \u2014 the gold standard in American medicine, in which half the study subjects get an inert vaccine and doctors, parents and patients did not know who got which.Salk himself objected to the use of a placebo during the clinical trial; he couldn\u2019t imagine depriving a child of a lifesaving vaccine. As the petition before the F.D.A. notes, the current vaccine, manufactured by Sanofi, was not tested against a placebo; scientists and doctors almost universally agree that withholding a lifesaving vaccine would be unethical.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and\u00a0log into\u00a0your Times account, or\u00a0subscribe\u00a0for all of The Times.Thank you for your patience while we verify access.Already a subscriber?\u00a0Log in.Want all of The Times?\u00a0Subscribe.<\/p>\n","protected":false},"author":1,"featured_media":18345,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-18343","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle"],"_links":{"self":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/18343","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18343"}],"version-history":[{"count":2,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/18343\/revisions"}],"predecessor-version":[{"id":18346,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/18343\/revisions\/18346"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/media\/18345"}],"wp:attachment":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18343"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18343"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18343"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}