{"id":15158,"date":"2024-10-21T21:27:36","date_gmt":"2024-10-21T21:27:36","guid":{"rendered":"http:\/\/medexperts.pro\/?p=15158"},"modified":"2024-10-22T18:41:04","modified_gmt":"2024-10-22T18:41:04","slug":"bruce-ames-95-dies-biochemist-discovered-test-for-toxic-chemicals","status":"publish","type":"post","link":"https:\/\/medexperts.pro\/?p=15158","title":{"rendered":"Bruce Ames, 95, Dies; Biochemist Discovered Test for Toxic Chemicals"},"content":{"rendered":"<div><\/div>\n<p id=\"article-summary\" class=\"css-79rysd e1wiw3jv0\">The Ames Test offered a fast and inexpensive way to identify carcinogens, leading to the banning of chemicals linked to cancer and birth defects.<\/p>\n<section class=\"meteredContent css-1r7ky0e\">\n<div class=\"css-s99gbd StoryBodyCompanionColumn\" data-testid=\"companionColumn-0\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">Bruce Nathan Ames, a biochemist who discovered a revolutionary method of detecting potential carcinogens, paving the way for the banning of many commonly used chemicals, died on Oct. 5 in Berkeley, Calif. He was 95.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">His wife, Giovanna Ferro-Luzzi Ames, said his death, in a hospital, was from complications after a fall.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The so-called Ames Test, developed in the 1970s, is still used by drug manufacturers and pesticide companies to check the safety of their products. It involves exposing chemicals to a mutant strain of salmonella bacteria that Dr. Ames created; how the bacteria responds to a chemical makes it possible to determine whether that chemical caused DNA damage and therefore might lead to cancer in humans.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">In an America increasingly concerned about the effects of pollution and industrial chemicals, the test offered a quick, inexpensive alternative to animal testing, which was so prohibitively expensive that regulators were able to test only a fraction of chemicals on the market.<\/p>\n<\/div>\n<\/div>\n<div data-testid=\"Dropzone-1\"><\/div>\n<div class=\"css-s99gbd StoryBodyCompanionColumn\" data-testid=\"companionColumn-1\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">\u201cIt changed the regulatory sphere,\u201d said Angela Creager, a science historian at Princeton University who is writing a book about the Ames Test. \u201cIt showed that it was actually possible to get toxicity information on every chemical if we wanted to<em class=\"css-2fg4z9 e1gzwzxm0\">.\u201d<\/em><\/p>\n<p class=\"css-at9mc1 evys1bk0\">After capturing the attention of the national press, Dr. Ames remained in the spotlight as he used the Ames Test to expose the toxicity of a number of commonplace chemicals.<\/p>\n<div class=\"css-1336jj\">\n<div class=\"css-121kum4\">\n<div class=\"css-171d1bw\"><\/div>\n<div class=\"css-asuuk5\">\n<div class=\"css-7axq9l\" data-testid=\"optimistic-truncator-noscript\">\n<div data-testid=\"optimistic-truncator-noscript-message\" class=\"css-6yo1no\">\n<p class=\"css-3kpklk\">We are having trouble retrieving the article content.<\/p>\n<p class=\"css-3kpklk\">Please enable JavaScript in your browser settings.<\/p>\n<\/div>\n<\/div>\n<div class=\"css-1dv1kvn\" id=\"optimistic-truncator-a11y\">\n<hr \/>\n<p>Thank you for your patience while we verify access. If you are in Reader mode please exit and\u00a0<a href=\"https:\/\/myaccount.nytimes.com\/auth\/login?response_type=cookie&amp;client_id=vi&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F10%2F21%2Fhealth%2Fbruce-ames-dead.html&amp;asset=opttrunc\">log into<\/a>\u00a0your Times account, or\u00a0<a href=\"https:\/\/www.nytimes.com\/subscription?campaignId=89WYR&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F10%2F21%2Fhealth%2Fbruce-ames-dead.html\">subscribe<\/a>\u00a0for all of The Times.<\/p>\n<hr \/>\n<\/div>\n<div class=\"css-1g71tqy\">\n<div data-testid=\"optimistic-truncator-message\" class=\"css-6yo1no\">\n<p class=\"css-3kpklk\">Thank you for your patience while we verify access.<\/p>\n<p class=\"css-3kpklk\">Already a subscriber?\u00a0<a data-testid=\"log-in-link\" class=\"css-z5ryv4\" href=\"https:\/\/myaccount.nytimes.com\/auth\/login?response_type=cookie&amp;client_id=vi&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F10%2F21%2Fhealth%2Fbruce-ames-dead.html&amp;asset=opttrunc\">Log in<\/a>.<\/p>\n<p class=\"css-3kpklk\">Want all of The Times?\u00a0<a data-testid=\"subscribe-link\" class=\"css-z5ryv4\" href=\"https:\/\/www.nytimes.com\/subscription?campaignId=89WYR&amp;redirect_uri=https%3A%2F%2Fwww.nytimes.com%2F2024%2F10%2F21%2Fhealth%2Fbruce-ames-dead.html\">Subscribe<\/a>.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>The Ames Test offered a fast and inexpensive way to identify carcinogens, leading to the banning of chemicals linked to cancer and birth defects.Bruce Nathan Ames, a biochemist who discovered a revolutionary method of detecting potential carcinogens, paving the way for the banning of many commonly used chemicals, died on Oct. 5 in Berkeley, Calif. He was 95.His wife, Giovanna Ferro-Luzzi Ames, said his death, in a hospital, was from complications after a fall.The so-called Ames Test, developed in the 1970s, is still used by drug manufacturers and pesticide companies to check the safety of their products. It involves exposing chemicals to a mutant strain of salmonella bacteria that Dr. Ames created; how the bacteria responds to a chemical makes it possible to determine whether that chemical caused DNA damage and therefore might lead to cancer in humans.In an America increasingly concerned about the effects of pollution and industrial chemicals, the test offered a quick, inexpensive alternative to animal testing, which was so prohibitively expensive that regulators were able to test only a fraction of chemicals on the market.\u201cIt changed the regulatory sphere,\u201d said Angela Creager, a science historian at Princeton University who is writing a book about the Ames Test. \u201cIt showed that it was actually possible to get toxicity information on every chemical if we wanted to.\u201dAfter capturing the attention of the national press, Dr. Ames remained in the spotlight as he used the Ames Test to expose the toxicity of a number of commonplace chemicals.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and\u00a0log into\u00a0your Times account, or\u00a0subscribe\u00a0for all of The Times.Thank you for your patience while we verify access.Already a subscriber?\u00a0Log in.Want all of The Times?\u00a0Subscribe.<\/p>\n","protected":false},"author":1,"featured_media":15160,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-15158","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle"],"_links":{"self":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/15158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=15158"}],"version-history":[{"count":2,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/15158\/revisions"}],"predecessor-version":[{"id":15161,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/posts\/15158\/revisions\/15161"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=\/wp\/v2\/media\/15160"}],"wp:attachment":[{"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=15158"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=15158"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medexperts.pro\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=15158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}