During his first term, President Donald J. Trump unveiled a bold initiative to end the H.I.V. epidemic in the United States by 2030 by focusing on 57 jurisdictions with the most urgent needs.

The plan, which Mr. Trump announced in 2019 at a State of the Union address, surprised advocacy groups. But it was widely lauded, and successful.

By 2022, the plan had driven down new infections nationwide by 30 percent in adolescents and young adults, and by roughly 10 percent in most other groups.

This time around, the Trump administration’s stance on H.I.V. appears to be much the opposite.

The Department of Health and Human Services is now considering shutting down the H.I.V. prevention division of the Centers for Disease Control and Prevention and shifting some of its activities to a different agency, according to federal officials.

The C.D.C. provides funds to states and territories for detecting and responding to H.I.V. outbreaks, prevention, syringe exchange, expanded testing in emergency rooms and education and awareness. Roughly one in four new diagnoses of H.I.V. is made with agency funds.

The administration’s plan has not yet been finalized, and its potential timing is unclear.

“It’s not 100 percent going to happen, but 100 percent being discussed,” said a federal official who was not authorized to speak to the media about the matter.

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